Protein Electrophoresis, Serum
This test measures the different types of proteins in your blood serum using electrophoresis, a technique that separates proteins based on size and electrical charge.
["Protein electrophoresis helps identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or kidney problems."]
Key facts at a glance
- LOINC
- 35319-3
- Short code
- Prot sp5 p sincalide Fld-mCnc
- Synonyms
- Prot sp5 p sincalide Fld-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Protein Electrophoresis Used For?
Protein electrophoresis is primarily used to detect and monitor conditions affecting protein production or distribution in the blood. It can help diagnose diseases like multiple myeloma (a cancer of plasma cells), certain liver diseases, and kidney disorders. It may also be used to evaluate protein abnormalities in hereditary conditions or to assess treatment responses in patients with chronic diseases.
How Is This Test Performed?
A small blood sample is drawn from your arm into a tube. The serum portion (liquid part of blood after clotting) is then separated and placed in a gel. An electric current is applied, causing proteins to move toward the opposite charge. After separation, the proteins are stained and visualized to create a pattern of bands, each representing different protein types.
What Does the Test Result Mean?
The test result shows a visual pattern of bands across the gel, with each band corresponding to a specific protein group. Abnormal patterns, such as extra bands, missing bands, or uneven distribution, may indicate underlying health issues that require further medical evaluation.
Preparation Before the Test
No special preparation is needed for this test. You may eat and drink normally before your blood draw. If you are on blood thinners or have a history of bleeding disorders, inform your healthcare provider beforehand.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Protein Electrophoresis
Frequently asked questions
Why might my doctor order this test?
What are common reasons for abnormal results?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy