Protein Electrophoresis (Serum/Plasma)
This test measures the different types of proteins in your blood, helping identify abnormalities in protein distribution that may signal conditions like kidney disease, liver problems, or certain cancers.
["Protein electrophoresis helps diagnose and monitor conditions affecting protein balance in your blood."]
Key facts at a glance
- LOINC
- 76668-3
- Short code
- Prot tube4 CSF-mCnc
- Synonyms
- Prot tube4 CSF-mCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What Proteins Are Measured?
Electrophoresis separates blood proteins based on size and electrical charge, revealing distinct bands corresponding to albumin, globulins (including alpha, beta, and gamma globulins), and other proteins. These bands reflect the overall protein composition and can highlight imbalances.
Common Uses and Conditions Monitored
This test is often used to detect conditions such as multiple myeloma, liver disease, kidney disease, and certain autoimmune disorders. It may also help evaluate protein malnutrition or monitor treatment responses.
How the Test Works
A small blood sample is drawn and placed in an electric field. Proteins migrate toward the opposite charge, creating visible bands when stained. The pattern and density of these bands indicate protein levels and types.
Preparation and Sample Collection
No special preparation is needed, but fasting may be advised depending on your doctor’s instructions. A blood sample is taken from a vein, usually in your arm, and sent to the lab for analysis.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal electrophoresis patterns can signal underlying health issues, such as elevated or low levels of specific proteins. For example, an increased gamma globulin fraction may suggest multiple myeloma or other immune-related disorders, while abnormal albumin levels could indicate liver or kidney disease. Early detection helps guide treatment decisions.
Short name
Protein Electrophoresis
Frequently asked questions
Why might my doctor order this test?
What does it mean if my results are abnormal?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy