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Protein Electrophoresis (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood, helping identify abnormalities in protein distribution that may signal conditions like kidney disease, liver issues, or certain cancers.

Quick summary

["Protein electrophoresis helps diagnose and monitor blood disorders by revealing imbalances in protein levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2888-6
Short code
Prot Ur-mCnc
Synonyms
Prot Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Proteins Are Measured?

Electrophoresis separates blood proteins based on their electrical charge and size. Key protein bands include albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal patterns may indicate conditions like multiple myeloma, nephrotic syndrome, or chronic inflammation.

Why Is This Test Done?

Your doctor may order this test to investigate symptoms like unexplained weight loss, swelling, fatigue, or signs of organ dysfunction. It’s also used to monitor conditions like kidney disease or autoimmune disorders.

Common Conditions Linked to Results

High or low levels of specific protein bands can signal underlying health issues. For example, elevated gamma-globulins may suggest immune system problems, while abnormal albumin levels could point to liver or kidney disease.

Sample Collection and Preparation

A blood sample is drawn from your arm, and the serum or plasma is separated for testing. This test typically requires no special preparation, but fasting may be advised depending on your doctor’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 24 to 48 hours, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
No special diet is required for this test, but always follow your doctor’s instructions. If fasting is advised for another reason, avoid eating or drinking anything except water.
What if my results are outside the expected range?
If your results show unusual protein patterns, your doctor will review them with you to determine the next steps, which may include additional tests or treatments.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy