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Protein Electrophoresis, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood, including albumin and globulins, which help your body function properly.

Quick summary

["Understanding your protein levels can help identify health issues like kidney problems or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53525-2
Short code
Prot Ur Ql SSA
Synonyms
Prot Ur Ql SSA
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ssa
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to check for conditions affecting protein balance, such as kidney disease, liver problems, or certain types of cancer. It can also help diagnose or monitor conditions like multiple myeloma or autoimmune diseases.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if blood is drawn from a vein. If you have a vein access issue, you might be asked to fast to improve blood flow.

What Happens During the Test

A healthcare provider will draw blood from a vein in your arm. The blood is then sent to a lab where it is separated into different protein fractions using gel electrophoresis.

What the Results Mean

Results show the distribution of proteins, such as albumin (the most abundant protein) and various globulins (proteins like antibodies). Abnormal patterns may indicate conditions like protein loss in urine, liver disease, or immune system disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Protein Electrophoresis

Frequently asked questions

What does a protein electrophoresis test measure?
This test measures the types and amounts of proteins in your blood, including albumin and different types of globulins. It helps identify patterns that may indicate health issues like kidney disease, liver problems, or immune disorders.
How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on lab processing times. Follow-up with your healthcare provider to discuss findings.
Can I eat or drink before this test?
If blood is drawn from a vein, fasting for 8–12 hours before the test may improve blood flow. If fasting isn’t required, stick to your usual diet unless instructed otherwise.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy