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Anti-Ro (SSA) Antibody, Serum Immunoassay (Screen)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies against the Ro (SSA) antigen, which may be linked to certain autoimmune conditions.

Quick summary

["Screening for antibodies that could indicate autoimmune disorders like lupus or Sjogren’s syndrome."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74304-7
Short code
PRRSV NAb Titr Ser Nt
Synonyms
PRRSV NAb Titr Ser Nt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
neut
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of anti-Ro (SSA) antibodies in your serum. These antibodies target proteins found in healthy cells, and their presence may signal an autoimmune response. This screening helps identify potential conditions where the immune system mistakenly attacks the body’s own tissues.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, joint pain, dry eyes, or mouth, or if you have a family history of autoimmune diseases. It’s also used in monitoring certain conditions like lupus or Sjogren’s syndrome.

Common Symptoms Linked to This Test

Symptoms that might prompt this test include chronic fatigue, unexplained fever, joint or muscle pain, dry skin or eyes, or a rash. If you experience these symptoms, discuss them with your doctor, as they could be related to conditions this test helps identify.

How the Test Works

The test uses a blood sample to detect specific antibodies. A small amount of your blood is drawn and analyzed in a lab to check for the presence of anti-Ro (SSA) antibodies. The result helps determine if further evaluation for autoimmune conditions is needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Anti-SSA Antibody (Screen)

Frequently asked questions

What does a positive result mean?
A positive screening result for anti-Ro (SSA) antibodies suggests a higher likelihood of an autoimmune condition, but it doesn’t confirm a diagnosis. Follow-up testing and clinical evaluation are required to determine the exact cause of your symptoms.
Can this test be used to diagnose autoimmune diseases?
No, this test is a screening tool. It helps identify potential risk but isn’t definitive on its own. Your doctor will use the results alongside other tests and symptoms to make a diagnosis.
How often should I get this test?
Frequency depends on your medical history and symptoms. Your healthcare provider will decide based on your individual needs, possibly recommending follow-up tests or monitoring over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy