Protein Electrophoresis (Serum) with Specific Protein Quantification
This test measures the different types of proteins in your blood, including albumin and globulins, often used to diagnose conditions like kidney disease, liver problems, or multiple myeloma.
["Helps identify abnormal protein patterns that may signal underlying health issues."]
Key facts at a glance
- LOINC
- 112016-1
- Short code
- Prs or abs of non-lftng sgn Endscpy
- Synonyms
- Prs or abs of non-lftng sgn Endscpy
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- endoscopy
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test to check for conditions affecting protein balance in your blood, such as kidney disease (e.g., nephrotic syndrome), liver disease, or certain cancers. It can also help monitor treatment responses for conditions like multiple myeloma or autoimmune disorders.
What to Expect Before the Test
No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your provider specifies it, but this is not always required. Bring any medications you’re currently taking to your appointment.
During the Test
A blood sample will be drawn from a vein in your arm. The process is quick and typically painless. You may feel a slight pinch, but most people tolerate it well. The blood is then sent to a lab for analysis.
What the Results Mean
Results show the distribution of proteins in your serum, including albumin and various globulins. Abnormal patterns may indicate conditions like protein-losing disorders, infections, or metabolic diseases. Your provider will interpret the results in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Protein electrophoresis is critical for diagnosing conditions like multiple myeloma (a cancer of plasma cells), kidney diseases (e.g., nephrotic syndrome), and liver disorders. It also helps detect abnormalities in protein synthesis or breakdown, such as those seen in autoimmune diseases or chronic infections. By identifying shifts in protein levels, providers can tailor treatments to address the root cause.
Short name
Serum Protein Electrophoresis
Frequently asked questions
What does an abnormal protein electrophoresis result mean?
How long does it take to get my results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy