Serum Protein Electrophoresis (Qualitative)
This test measures the different types of proteins in your blood using electrophoresis, a method that separates proteins based on size and charge.
["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or other disorders."]
Key facts at a glance
- LOINC
- 47738-0
- Short code
- PSA Fld-mCnc
- Synonyms
- PSA Fld-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 4
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84153
- SNOMED
- 39392002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates blood proteins into distinct bands, each representing different protein groups (e.g., albumin, alpha-globulins, beta-globulins, gamma-globulins). Abnormal bands or patterns may indicate underlying health issues.
Common Uses and Indications
Doctors may order this test to diagnose or monitor conditions such as multiple myeloma, lymphoma, liver disease, kidney disease, or certain autoimmune disorders. It’s also used to screen for genetic disorders affecting protein synthesis.
Sample Preparation and Collection
A blood sample is drawn from a vein, typically in your arm. The serum (liquid part of blood after clotting) is then analyzed in a lab using electrophoresis.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for a few hours before the test if instructed by your healthcare provider. Wear comfortable clothing and avoid heavy meals.
Reference range
Normal: <4.0 ng/mLN/A
No special preparation required. For PSA, avoid sexual activity for 24-48 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein patterns can reveal conditions like monoclonal gammopathy (e.g., multiple myeloma), where an abnormal protein (M-protein) appears in the gamma-globulin region. Low albumin levels may indicate liver or kidney disease, while elevated globulins could signal inflammation or immune system disorders.
Short name
Serum Protein Electrophoresis
Frequently asked questions
Why might my doctor recommend this test?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy