Serum Free Salivary Monoclonal Protein Concentration
This test measures the amount of a specific protein (monoclonal) found only in your saliva, excluding any proteins bound to other substances. It helps identify unusual protein patterns that may indicate conditions like certain cancers or immune system disorders.
["This test helps detect abnormal protein production that may signal underlying health concerns."]
Key facts at a glance
- LOINC
- 19206-2
- Short code
- PSA Free Smn-sCnc
- Synonyms
- PSA Free Smn-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 4
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84153
- SNOMED
- 39392002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you have symptoms like persistent mouth sores, unexplained weight loss, or a history of conditions such as multiple myeloma or lymphoma. It may also be used as part of a broader evaluation for certain autoimmune diseases or to monitor treatment responses.
What Does the Test Involve?
You will provide a saliva sample, typically collected by gently rolling a cotton swab in your mouth for a few seconds. The sample is then sent to a lab for analysis. No fasting is required.
What Are Possible Results?
Results are interpreted based on the concentration of the specific monoclonal protein detected. Abnormal levels may suggest conditions requiring further medical evaluation.
What Does It Mean If Results Are Abnormal?
Abnormal results may indicate the presence of a monoclonal protein that could be linked to conditions such as plasma cell dyscrasias (e.g., multiple myeloma) or other systemic diseases. Your doctor will discuss these findings with you and may recommend additional tests or treatments.
Reference range
Normal: <4.0 ng/mLN/A
No special preparation required. For PSA, avoid sexual activity for 24-48 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Free monoclonal protein in saliva
Frequently asked questions
What preparation do I need before the test?
How long will it take to get my results?
Can I have a follow-up test if my results are abnormal?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy