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Serum or Plasma Mass Concentration of Albumin

Published: August 9, 2026Updated: August 16, 2026

Albumin is a protein found in your blood that helps maintain fluid balance and supports immune function. Your doctor may check your albumin level to assess how well your body is retaining fluids or to monitor conditions like kidney disease or liver problems.

Quick summary

["Albumin helps keep fluids in your blood vessels and supports healing; low levels may signal fluid loss or organ dysfunction."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
19198-1
Short code
PSA Smn-aCnc
Synonyms
PSA Smn-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
4
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84153
SNOMED
39392002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Albumin Levels Matter

Albumin plays a critical role in your body’s ability to transport nutrients, regulate blood pressure, and support immune responses. It’s also a key indicator of how well your kidneys and liver are functioning. Low albumin levels can sometimes suggest conditions like chronic kidney disease, liver cirrhosis, or severe dehydration.

What Causes Albumin Levels to Change?

Albumin levels can drop due to conditions like kidney disease, liver disease, malnutrition, or severe infections. Conversely, high levels might occur in certain genetic disorders or during pregnancy. Your doctor may also check albumin as part of a broader health assessment.

How Is Albumin Tested?

This test measures the amount of albumin protein in your blood, typically collected from serum or plasma. The test is usually done through a simple blood draw and analyzed using a specialized laboratory method to determine its concentration.

What Does Your Albumin Result Mean?

Results are interpreted based on your overall health and medical history. Low albumin may prompt further testing for conditions like kidney or liver disease, while high levels may need investigation into underlying causes like dehydration or genetic factors.

Reference range

Normal: <4.0 ng/mLN/A

Specimen: serum

No special preparation required. For PSA, avoid sexual activity for 24-48 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Albumin Levels and Health

Short name

Albumin Level

Frequently asked questions

What are the normal reference ranges for albumin?
Albumin reference ranges can vary slightly by lab and individual health status. Typically, healthy adults have albumin levels between approximately 3.4 to 5.4 grams per deciliter (g/dL) in serum or plasma. Your doctor will use these guidelines in combination with your clinical picture to interpret your results.
Can diet affect my albumin test results?
Yes, diet can influence albumin levels. Eating a balanced diet rich in protein and avoiding excessive alcohol or malnutrition may help maintain stable albumin levels. However, your doctor will consider your overall health and medical history when evaluating your results.
How often should I get this test?
The frequency of albumin testing depends on your health condition. People with chronic kidney disease, liver disease, or other conditions affecting protein levels may need regular monitoring. Your healthcare provider will determine the best schedule for you based on your specific needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy