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Pseudouridine-to-Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that measures pseudouridine relative to creatinine, helping account for differences in urine concentration.

Quick summary

["This ratio measures urinary pseudouridine in a form adjusted for urine concentration."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78692-1
Short code
Pseudouridine/Creat Ur-sRto
Synonyms
Pseudouridine/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of pseudouridine in urine relative to the amount of creatinine. Pseudouridine is a modified nucleoside produced during normal cellular metabolism and RNA processing.

Why might I need this test?

The test may be used in specialized clinical studies or investigations of altered nucleoside metabolism. It is not commonly ordered as a routine screening test, so the reason for testing should be discussed with the ordering clinician.

How is the test performed?

A urine specimen is collected and analyzed in a laboratory for both pseudouridine and creatinine. The laboratory then calculates their ratio. Collection instructions may call for a spot urine sample or a timed collection.

How do I prepare for the test?

Follow the laboratory's instructions about collection timing, container type, and the amount of urine needed. Do not change your diet, fluid intake, or medications unless your healthcare professional specifically advises you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine pseudouridine/creatinine ratio

Frequently asked questions

Does this test measure kidney function?
No. Creatinine is used to help adjust the urine pseudouridine measurement for urine concentration, but this test is not a standard kidney-function test.
Is this a common cancer screening test?
No. It is generally used in specialized evaluation or research and should not be used alone to screen for or diagnose cancer.
What if my result is outside the expected range?
An out-of-range result does not by itself establish a disease. Your clinician should interpret it alongside symptoms, medical history, kidney function, and other relevant tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy