Protein Electrophoresis (Serum) with Bromocresol Green (BCG) Dye

What Proteins Does This Test Measure?

Protein electrophoresis separates blood proteins into fractions based on size and charge. The BCG dye helps visualize these fractions, showing how much of each protein (like albumin, globulins, and others) is present. This can reveal patterns that may not be visible with standard protein tests alone.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test if you have symptoms like swelling, unexplained weight loss, fatigue, or if they suspect conditions such as multiple myeloma, kidney disease, or liver disorders. It can also help monitor treatment progress for certain diseases.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The serum portion is separated and placed in a gel. An electric current is applied to move proteins through the gel, creating bands that represent different protein types. The BCG dye stains these bands for analysis.

What Are Common Findings?

Typical results show bands corresponding to albumin (usually the largest, most abundant protein), globulins (which include antibodies and other proteins), and sometimes smaller proteins. Abnormal patterns may indicate low albumin (common in kidney or liver disease), high globulin levels (possible infection, inflammation, or cancer), or unusual bands suggesting genetic disorders.