Serum Protein Electrophoresis (Qualitative)
This test measures the different types of proteins in your blood using electrophoresis, a method that separates proteins based on size and charge.
["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma or other blood disorders."]
Key facts at a glance
- LOINC
- 14246-3
- Short code
- PS IgM Ser-aCnc
- Synonyms
- PS IgM Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Protein Electrophoresis Used For?
Protein electrophoresis is primarily used to detect and monitor conditions affecting protein levels in the blood. It can help identify abnormal protein bands that might indicate diseases such as multiple myeloma, lymphoma, or other blood disorders. This test is often part of a broader diagnostic workup for unexplained symptoms like fatigue, weight loss, or unexplained anemia.
How Is This Test Performed?
A small blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum, which is analyzed using electrophoresis. The results show distinct bands representing different protein fractions, including albumin, alpha, beta, and gamma globulins.
Preparation for the Test
No special preparation is needed for this test. However, if you are on certain medications that affect protein levels, your healthcare provider may advise you to stop them temporarily or adjust your timing.
What Are Common Findings?
Normal results show a balanced distribution of protein bands. Abnormal findings may include an increased or decreased amount of specific proteins, such as monoclonal spikes (seen in multiple myeloma) or altered ratios of albumin to globulins.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Protein electrophoresis is crucial for diagnosing and managing conditions like multiple myeloma, where an abnormal protein (monoclonal gammopathy) is produced. It can also help evaluate other conditions affecting protein synthesis or breakdown, such as liver disease, kidney disease, or inflammatory disorders. Early detection can guide treatment decisions and improve patient outcomes.
Short name
Protein Electrophoresis
Frequently asked questions
Why might my doctor order this test?
What does a positive or abnormal result mean?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy