Skip to content

Serum or Plasma Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types and amounts of proteins in your blood, separated by size and charge. It helps identify abnormalities in protein distribution, which may signal conditions like multiple myeloma, liver disease, or other disorders.

Quick summary

["This test helps doctors check for unusual protein patterns that could indicate health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11569-1
Short code
PS IgM Ser Ql
Synonyms
PS IgM Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to investigate symptoms such as unexplained weight loss, fatigue, swelling, or changes in urine appearance. It’s also used to monitor conditions like kidney disease, liver problems, or certain cancers where protein levels may be affected.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood, or a blood sample may be collected from a vein. If you’re on blood thinners, let your doctor know before the test.

What Happens During the Test?

A small amount of blood is collected and placed on a special gel. An electric current is applied to separate proteins into bands based on their size and charge. The results are analyzed to see if any patterns are abnormal.

What Are Possible Results?

Normal results show a typical distribution of proteins (albumin, globulins, etc.). Abnormal results may show unusual bands, high or low levels of specific proteins, or shifts in protein distribution, which can signal underlying health concerns.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis

Frequently asked questions

Abnormal protein electrophoresis can indicate conditions such as multiple myeloma (a cancer of plasma cells), liver disease, kidney disease, or inflammatory disorders. It may also help diagnose or monitor conditions like amyloidosis or certain autoimmune diseases.
This test is primarily qualitative, so it doesn’t provide exact numeric values but rather visual patterns. Your doctor will interpret the results in the context of your symptoms and medical history.
Will I need to fast before this test?
No fasting is required for this test. Unlike some blood tests, protein electrophoresis doesn’t depend on dietary restrictions.
How long will it take to get my results?
Results are typically available within a few days to a week, depending on your lab’s processing time. Your doctor will discuss them with you during a follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy