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Serum Pigment Concentration (Bilirubin, Biliverdin, or Related Pigments)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain natural pigments in your blood, often linked to liver function or red blood cell breakdown. It helps assess conditions affecting bile flow or hemolysis.

Quick summary

["Your blood may contain abnormal pigments if you have liver issues, gallbladder problems, or conditions that break down red blood cells too quickly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77216-0
Short code
PSP IgM Ser IA-aCnc
Synonyms
PSP IgM Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects levels of bilirubin (yellow pigment from red blood cell breakdown) and biliverdin (a greenish pigment formed from bilirubin). These pigments can indicate whether your liver is processing them normally or if there’s an excess from conditions like jaundice, liver disease, or hemolytic anemia.

Why It Matters in Your Body

High levels of these pigments can signal problems like bile duct blockages, liver inflammation, or red blood cell destruction. Low levels may suggest certain metabolic or genetic disorders.

Common Conditions It Helps Diagnose

This test is often used alongside others to diagnose jaundice, liver diseases (like hepatitis), gallbladder issues, or conditions causing excessive red blood cell breakdown (e.g., hemolytic anemia).

A blood sample is drawn from a vein, typically in your arm. The serum (liquid part of blood after clotting) is analyzed for pigment levels. No special preparation is needed, but avoid alcohol or heavy meals 12–24 hours before testing.

This test is usually done when symptoms like yellowing of skin/eyes (jaundice), dark urine, or fatigue appear. It may also be part of routine liver function checks.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Bilirubin/Biliverdin Profile

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab. Follow-up with your healthcare provider to discuss findings.
Can I eat or drink anything before this test?
No special diet is required, but avoid alcohol or heavy meals 12–24 hours before your appointment to ensure accurate results.
What if my results are outside the normal range?
Your doctor will explain what the results mean in the context of your symptoms and medical history. High levels may prompt further testing for liver or bile duct issues, while low levels may need additional evaluation for rare conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy