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Plasma Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and amounts of proteins in your blood plasma using electrophoresis, a method that separates proteins based on size and charge.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or other blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51626-0
Short code
PT 1:4 NP 1h separate PPP
Synonyms
PT 1:4 NP 1h separate PPP
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag-tissue-factor-induced-factor-substitution-after-addition-of-normal-plasma-h-post-incubation-separate-tubes
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins into distinct bands (fractions) based on their electrical charge and molecular weight. Key fractions include albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal patterns may indicate conditions affecting protein production or breakdown.

Why It’s Ordered

Your healthcare provider may order this test to diagnose or monitor conditions such as multiple myeloma, Waldenström macroglobulinemia, liver disease, or other protein-related disorders. It’s also used in screening for certain genetic or metabolic disorders.

Sample Preparation

A blood sample is drawn from a vein, typically in the arm. Plasma is separated from blood cells and prepared for electrophoresis. The test is qualitative, meaning it provides a visual pattern rather than specific numeric values.

Common Conditions Monitored

Abnormal results may show increased or decreased levels of specific protein fractions. For example, a high gamma-globulin fraction could suggest immune system disorders, while unusual bands may indicate myeloma or other malignancies.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Qualitative Protein Electrophoresis

Frequently asked questions

What Does It Mean If My Results Are Abnormal?
Abnormal patterns may signal underlying health issues like multiple myeloma (excess monoclonal proteins), liver disease (altered albumin/globulin ratios), or other conditions affecting protein synthesis or clearance. Always discuss results with your provider for personalized interpretation.
How Long Does It Take to Get Results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up may require additional testing or consultation with your healthcare provider.
Can I Fast Before This Test?
No fasting is required for this test. However, inform your provider about any medications or conditions that could affect protein levels, such as kidney disease or liver issues.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy