Serum or plasma cholesterol and high-density lipoprotein (HDL) cholesterol ratio (qualitative screening)
This test measures the ratio of your HDL cholesterol to total cholesterol in your blood. HDL cholesterol is often called 'good' cholesterol because it helps remove other types of cholesterol from your bloodstream.
["Assessing your HDL cholesterol level relative to total cholesterol can help identify potential heart health risks."]
Key facts at a glance
- LOINC
- 40091-1
- Short code
- PT 1.5h p chal PPP
- Synonyms
- PT 1.5h p chal PPP
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 44
- Ref high
- 147
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- coag-tissue-factor-induced
- CPT
- 84075
- SNOMED
- 27550007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
HDL cholesterol plays a key role in protecting your heart by carrying excess cholesterol away from your arteries. A higher HDL ratio may suggest better cholesterol management, but it’s not the only factor in heart health. This screening helps doctors evaluate whether your cholesterol levels are balanced and if you may need lifestyle or medical interventions.
What to Expect During the Test
You’ll have a simple blood draw, usually taken from your arm. The sample is processed to measure both your total cholesterol and HDL cholesterol levels. Results are used to calculate the ratio, though this test is often used as a preliminary screening rather than a definitive measurement.
Common Causes for Testing
Doctors may order this test if you have risk factors for heart disease, such as high blood pressure, obesity, a family history of heart problems, or if you’re diagnosed with high cholesterol. It can also be part of routine check-ups for adults over 20 years old.
What the Results Mean
While this test provides a ratio, it’s not a standalone measure of heart health. A higher HDL ratio may indicate better cholesterol balance, but doctors will consider other factors like LDL cholesterol, triglycerides, and overall lifestyle. Results are discussed with your healthcare provider to guide next steps.
Reference range
Adult: 44-147 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HDL Cholesterol Ratio Screening
Frequently asked questions
What does a high or low HDL ratio mean for my health?
Will this test replace other cholesterol tests?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy