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Protein Electrophoresis (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood, helping identify abnormalities in protein distribution that may signal conditions like kidney disease, liver issues, or certain cancers.

Quick summary

["This test helps doctors diagnose and monitor conditions affecting protein levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33884-8
Short code
PT 1h NP Cont PPP Cont
Synonyms
PT 1h NP Cont PPP Cont
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag-tissue-factor-induced-factor-substitution-h-post-incubation-after-addition-of-normal-plasma
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Protein electrophoresis separates blood proteins into fractions—such as albumin, alpha-globulins, beta-globulins, and gamma-globulins—using an electric field. This helps detect unusual patterns that could indicate underlying health problems.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect conditions like multiple myeloma, liver disease, or kidney problems.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing. This test does not require fasting.

Common Conditions Monitored

Protein electrophoresis helps track conditions like chronic kidney disease, liver cirrhosis, or autoimmune disorders by observing shifts in protein bands.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum/Plasma Protein Electrophoresis

Frequently asked questions

What Are Normal Results?
Normal results show balanced protein bands, but specific ranges depend on the lab and individual health. Abnormal patterns may need further testing.
Can Diet Affect Results?
Dietary changes typically do not impact protein electrophoresis results, as it measures intrinsic blood protein composition.
How Long Does It Take to Get Results?
Results are usually available within 24 to 48 hours, depending on lab processing times.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy