Plasma Protein Electrophoresis (Qualitative)
This test measures the distribution of different protein fractions in your blood plasma using electrophoresis, a method that separates proteins based on size and charge.
["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma or other blood disorders."]
Key facts at a glance
- LOINC
- 33357-5
- Short code
- PT 1h p Inc PPP
- Synonyms
- PT 1h p Inc PPP
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- coag-tissue-factor-induced-factor-substitution-h-post-incubation
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates plasma proteins into five main bands: albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and gamma globulins. Each band represents a group of proteins with similar electrical charges and sizes.
How the Test Works
A small blood sample is drawn, and the plasma is applied to a gel. An electric current is applied, causing proteins to migrate toward the positive electrode. After separation, the gel is stained to visualize protein bands.
Common Conditions Evaluated
This test is often used to detect abnormalities in protein levels, such as elevated or low gamma globulins (seen in conditions like multiple myeloma or autoimmune diseases) or unusual bands that may indicate genetic disorders or metabolic issues.
Preparation and Sample Collection
No special preparation is needed. A blood sample is collected from a vein, typically in the arm. The plasma is then processed and sent to the lab for analysis.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Qualitative protein electrophoresis is critical for diagnosing and monitoring conditions affecting protein synthesis or breakdown. For example, it can help identify monoclonal gammopathies (abnormal protein spikes) linked to diseases like multiple myeloma or Waldenström macroglobulinemia. It may also assist in evaluating hereditary conditions like Fabry disease or other metabolic disorders where protein patterns deviate from normal.
Short name
Qualitative Protein Electrophoresis
Frequently asked questions
What does a qualitative protein electrophoresis test show?
How long does it take to get results from this test?
Can fasting affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy