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Serum Creatinine (Creatinine Level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps evaluate kidney function and detect early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33887-1
Short code
PT 2h NP PPP
Synonyms
PT 2h NP PPP
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag-tissue-factor-induced-factor-substitution-h-post-incubation-after-addition-of-normal-plasma
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out of your blood by your kidneys. High levels can indicate poor kidney function, while low levels may suggest overhydration or muscle wasting. This test is often used alongside other measures, like blood urea nitrogen (BUN), to assess kidney health.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood. If you’re on a low-protein diet or have had recent muscle activity, your doctor may advise timing your test to avoid temporary fluctuations in results.

Common Causes of Abnormal Results

Elevated creatinine levels may signal kidney disease, dehydration, or conditions affecting muscle metabolism (e.g., severe muscle injury or illness). Low levels could suggest dehydration, overhydration, or conditions like liver disease or malnutrition that reduce muscle mass.

What the Results Mean

Your results will be compared to a reference range provided by your healthcare team. While ranges vary by lab, they reflect typical values for healthy adults. Your doctor will interpret results in the context of your overall health, other tests, and symptoms you may have.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function. Chronic kidney disease (CKD) often shows up early with subtle changes in creatinine, so regular monitoring is important for people at higher risk (e.g., those with diabetes, hypertension, or a family history of kidney disease). It can also help guide treatment decisions, such as adjusting medications that affect kidney function.

Short name

None

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health status. For example, people with diabetes or hypertension may get it more frequently than others. Follow-up tests are often scheduled every 6–12 months if you have kidney concerns.
What can affect my creatinine test results?
Several factors can influence creatinine levels, including recent exercise, dehydration, muscle mass, or certain medications. If you’ve had recent surgery, illness, or changes in diet, let your doctor know so they can account for these factors when reviewing your results.
Do I need to fast for this test?
No fasting is required for a creatinine test. Unlike some other blood tests, it doesn’t depend on what you eat or drink before the draw.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy