Serum or plasma concentration of total protein
This test measures the amount of protein in your blood, which helps assess overall protein status and kidney function.
["Total protein levels can signal kidney health or nutritional needs."]
Key facts at a glance
- LOINC
- 33885-5
- Short code
- PT 2h p 1:4 NP PPP
- Synonyms
- PT 2h p 1:4 NP PPP
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- coag-tissue-factor-induced-factor-substitution-h-post-incubation-after-addition-of-normal-plasma
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done? Your healthcare provider may order this test to check how well your body is working, to look for signs of illness, or to monitor a condition you already have.
Doctors may order a total protein test to check for conditions like kidney disease, liver problems, malnutrition, or certain infections. It can also help monitor protein loss due to conditions like kidney failure or excessive sweating.
What Does the Result Mean? Your results show whether your values fall within the expected range. Results that are higher or lower than normal may point to a health issue that needs further evaluation by your provider.
Results are typically reported as a range, but they can vary based on factors like age, sex, and overall health. Low protein levels may indicate poor nutrition or organ dysfunction, while very high levels could suggest conditions like multiple myeloma or severe dehydration.
Common Conditions Affecting Results: Certain conditions, such as infections, dehydration, liver or kidney problems, and some long-term illnesses, can affect your results, as can medicines, supplements, and what you ate recently.
Low protein levels might be linked to malnutrition, kidney disease, or liver disorders. High levels could signal dehydration, inflammation, or certain blood disorders.
Sample Collection and Preparation: A trained staff member will collect your sample, usually a small amount of blood from a vein in your arm. Follow any special instructions from your provider, such as fasting, before your appointment.
This test uses blood drawn from a vein, usually in your arm. The blood is separated into serum (liquid part after clotting) or plasma (liquid part before clotting) for testing.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Total Protein
Frequently asked questions
Total protein levels are important for diagnosing and managing conditions affecting protein metabolism, kidney function, or overall health. Abnormal results may prompt further testing to identify underlying causes.
Results are usually available within 1 to 3 business days, depending on your lab’s processing schedule.
You may eat and drink normally before the test unless instructed otherwise by your healthcare provider.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy