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Plasma Fibrinogen Concentration (Quantitative)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fibrinogen in your blood plasma, a protein crucial for blood clotting.

Quick summary

["Fibrinogen helps your blood clot properly and supports wound healing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
49045-8
Short code
PT + aPTT + Fibrinogen Pnl PPP
Synonyms
PT + aPTT + Fibrinogen Pnl PPP
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
60 N/A – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like easy bruising, excessive bleeding, or if you’re at risk for blood clots. It can also be part of a general health check or to monitor conditions affecting clotting, such as liver disease or certain blood disorders.

What to Expect Before the Test

No special preparation is needed. You may fast for 8–12 hours before the test if instructed, but this is not always required. Bring any medications you’re taking to your appointment.

How the Test Works

A small blood sample is drawn from a vein, usually in your arm. The blood is processed to separate plasma, and the fibrinogen level is measured using a specialized lab technique.

What the Results Mean

Results are reported as a concentration value (e.g., grams per liter). Low levels may indicate bleeding disorders or liver issues, while very high levels could suggest inflammation, pregnancy, or certain blood disorders.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen is essential for blood clotting. Low levels can lead to excessive bleeding, while high levels may increase clot risk. Your doctor will interpret results in the context of your symptoms and medical history.

Short name

Fibrinogen Level

Frequently asked questions

What causes low fibrinogen?
Low fibrinogen can result from liver disease, severe infections, blood loss, or certain medications. It may also be inherited in some cases.
What causes high fibrinogen?
High fibrinogen is often linked to inflammation, pregnancy, or certain cancers. It can also be a reaction to stress or infection.
How often should I get this test?
Your doctor will determine the frequency based on your health needs. Regular monitoring may be needed if you have a condition affecting fibrinogen levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy