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Protein Electrophoresis, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and amounts of proteins in your blood serum, helping identify abnormalities in protein distribution that may signal conditions like kidney disease, liver issues, or certain cancers.

Quick summary

["This test helps doctors check for protein imbalances that could indicate health problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44138-6
Short code
PT Brain W RNC IV
Synonyms
PT Brain W RNC IV
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
pt
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to diagnose or monitor conditions such as multiple myeloma, kidney disease, liver disease, or other metabolic disorders. It can also help evaluate symptoms like unexplained weight loss, fatigue, or swelling.

What to Expect Before the Test

No special preparation is needed. You’ll typically provide a blood sample drawn from a vein in your arm. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results show the distribution of proteins (e.g., albumin, globulins) in your blood. Abnormal patterns may point to conditions like low albumin (which could indicate malnutrition or kidney problems) or high levels of certain globulins (which may signal infections, inflammation, or autoimmune diseases).

Common Conditions Linked to This Test

Abnormal results may suggest kidney disease, liver disease, multiple myeloma, or other protein-related disorders. Your doctor will interpret results in the context of your symptoms and medical history.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Protein Electrophoresis

Frequently asked questions

What does a protein electrophoresis test measure?
It measures the types and quantities of proteins in your blood, separated by size and charge. This helps identify patterns that may indicate underlying health issues.
How long does it take to get protein electrophoresis results?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Follow-up with your doctor to discuss findings.
Can diet affect protein electrophoresis results?
Dietary changes alone won’t alter the test results, but certain conditions (e.g., kidney disease) may require dietary adjustments to support overall health while managing symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy