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FDG PET/CT Skull and Thigh for Tumor Localization, Without Contrast

Published: August 9, 2026Updated: August 16, 2026

A PET/CT scan that uses radioactive FDG to help locate tumors in the skull and thigh. It is performed without iodinated IV contrast.

Quick summary

["This scan shows areas of abnormal FDG uptake that may help identify and locate a tumor, but findings require clinical interpretation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82808-7
Short code
PT+CT Skull-thigh Tum loc W FDG+WO contr
Synonyms
PT+CT Skull-thigh Tum loc W FDG+WO contr
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
pt-ct
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a positron emission tomography/computed tomography (PET/CT) scan used to help locate tumors. A radioactive tracer called fluorodeoxyglucose (FDG) is given before the scan, and PET imaging measures areas of increased tracer uptake while CT provides detailed anatomy.

Why might I need this test?

It may be ordered to evaluate a known or suspected tumor, identify the tissue taking up the most FDG, or help guide a biopsy, surgery, or other treatment. It may also be used to assess how a tumor responds to treatment.

How is the test performed?

After receiving FDG through a vein, you lie on a scanning table while the PET/CT machine collects images of the specified areas. The examination may take a longer time than a standard CT scan. Because the study is performed without iodinated IV contrast, a contrast-related reaction is less likely.

How do I prepare for the test?

The imaging center will provide specific instructions, which may include fasting for several hours and limiting strenuous exercise. Tell the care team about diabetes, medications, pregnancy or breastfeeding, allergies, and recent surgery, because any of these may affect preparation or image quality.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Increased FDG uptake may occur where a tumor is present, but it is not specific for cancer. Inflammation, infection, healing tissue, and some other conditions can also appear active on PET imaging. Low or absent uptake does not completely exclude a tumor, so results must be interpreted with the scan images, medical history, and other tests.

Short name

FDG PET/CT for Tumor Localization

Frequently asked questions

Does this test use contrast?
The study is performed without iodinated IV contrast, which is the dye commonly used for CT. You will still receive a small dose of the radioactive FDG tracer, so the scan involves radiation.
Can an abnormal PET/CT result confirm cancer?
No. PET/CT can show areas that may be suspicious and help determine where to look more closely, but tissue testing or other clinical evaluation may be needed to confirm a diagnosis.
Why might my blood sugar affect the result?
FDG uptake can be affected by blood glucose and recent physical activity. The imaging center may ask you to fast or check your glucose before the tracer is administered.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy