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Pterins in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain chemical compounds called pterins found in your cerebrospinal fluid (the fluid surrounding your brain and spinal cord). Pterins are involved in important biological processes, and their levels may be checked to help diagnose or monitor certain conditions.

Quick summary

["Pterins in CSF may help identify or track conditions affecting brain chemistry."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
80168-8
Short code
Pterins Pnl CSF
Synonyms
Pterins Pnl CSF
Category
coagulation
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test if they suspect a metabolic disorder, genetic condition, or neurological issue that affects pterin metabolism. It could also be part of a broader evaluation for symptoms like developmental delays, seizures, or movement disorders.

What Does the Test Involve?

A small amount of cerebrospinal fluid is collected through a procedure called a lumbar puncture (spinal tap). The fluid is then analyzed in a lab to measure pterin levels.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast or avoid certain medications. Inform your provider about any medications you’re taking, as they may affect results.

What to Expect During the Test

You’ll lie on your side with your knees bent. A needle is gently inserted into your lower back to collect fluid. You may feel pressure or a slight sting, but it’s usually brief. You’ll be given instructions to avoid straining or moving too much afterward.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: csf

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pterins in CSF

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your provider will discuss the findings with you during your follow-up visit.
What are common causes of abnormal pterin levels?
Abnormal pterin levels can result from genetic disorders affecting pterin metabolism, certain neurological conditions, or exposure to toxins. Rarely, they may also be linked to other metabolic or developmental issues.
Can diet affect pterin levels?
Dietary factors alone rarely affect pterin levels in CSF, as pterins are primarily metabolized within cells. However, if you’re taking medications or supplements, always check with your provider before stopping or changing them.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy