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Esophageal pH measurement (24-hour ambulatory monitoring)

Published: August 9, 2026Updated: August 16, 2026

This test measures how acidic or basic the acid in your stomach is while you sleep and throughout the day. It helps doctors check if stomach acid is flowing back into your esophagus too often, which can cause heartburn or acid reflux.

Quick summary

["This test helps diagnose and monitor conditions like GERD (acid reflux) and gastroesophageal reflux disease (GERD)."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57823-7
Short code
PT Esophagus W RNC IV
Synonyms
PT Esophagus W RNC IV
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
pt
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

A small tube called a pH sensor is placed in your esophagus during a short procedure. The sensor is connected to a small recording device worn on your belt. As you go about your normal activities, the device records pH levels in your stomach over 24 hours.

Preparation

No special preparation is needed for this test. You may eat and drink normally, but avoid taking any medications that could affect stomach acid (like certain antacids or heartburn medications) unless approved by your doctor. You’ll need to wear the recording device for a full day.

What to Expect During the Procedure

The procedure takes about 15 minutes. A doctor or nurse will insert the sensor through your nose into your esophagus. You may feel a slight discomfort or pressure, but it’s usually not painful. The sensor is then attached to the recording device, and you’ll be able to go home the same day.

Aftercare

After the test, you can return to your normal activities. Remove the recording device when you go to bed and return it to your doctor. Avoid removing the sensor yourself. If you experience any unusual symptoms like difficulty swallowing or severe pain, contact your doctor immediately.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing conditions like GERD, where stomach acid frequently flows back into the esophagus. It can also help determine if you have Barrett’s esophagus (a precancerous change in the lining of the esophagus) or other complications. Results help guide treatment plans, such as lifestyle changes, medications, or in severe cases, surgery.

Frequently asked questions

Why would my doctor recommend this test?
Your doctor may recommend this test if you frequently experience heartburn, chest pain, or trouble swallowing. It’s also used if you have symptoms like coughing, hoarseness, or asthma that don’t improve with usual treatments. This test helps rule out or confirm acid reflux-related issues.
What are the possible risks or side effects?
The most common side effect is a slight discomfort or mild irritation where the sensor is placed in your nose or throat. Rarely, there may be a small risk of infection or bleeding at the insertion site. Most people tolerate the test well, and the discomfort is usually temporary.
How long will I need to wear the recording device?
You’ll need to wear the recording device for a full 24-hour period to get accurate results. This allows the device to capture your stomach acid levels throughout the day and night, including when you sleep, which is when acid reflux often occurs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy