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Parathyroid Hormone, Active (PTH) - Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the active form of parathyroid hormone (PTH) in your blood, which helps regulate calcium levels in your body.

Quick summary

["Active PTH helps balance calcium and phosphate, affecting bone health and nerve function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63301-6
Short code
PTH Ab Ser Ql IF
Synonyms
PTH Ab Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order an active PTH test to check for conditions affecting calcium metabolism, such as hypoparathyroidism (low PTH), hyperparathyroidism (high PTH), or kidney disease. It can also help diagnose or monitor conditions like osteoporosis, kidney stones, or vitamin D deficiency.

What Does the Test Involve?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab for analysis using a specialized immunoassay method to measure the active PTH level.

What to Expect Before the Test

No special preparation is needed for this test. You may eat and drink normally before the blood draw. If you are on certain medications that affect calcium or PTH, inform your healthcare provider before the test.

What Are Possible Results?

Results are interpreted by your healthcare provider based on your overall health, symptoms, and medical history. Abnormal results may indicate imbalances in calcium or PTH levels that need further evaluation.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Active PTH is crucial for maintaining calcium homeostasis. Low levels may suggest hypoparathyroidism, while elevated levels can point to hyperparathyroidism or other metabolic disorders. Monitoring PTH levels helps manage conditions affecting bone density, kidney function, and nerve signaling.

Short name

Active PTH

Frequently asked questions

What causes abnormal PTH levels?
Abnormal PTH levels can result from conditions like kidney disease, vitamin D deficiency, or tumors affecting the parathyroid glands. Medications, such as certain diuretics or calcium supplements, may also influence PTH levels.
How often should I get this test?
Your doctor will determine the frequency based on your health needs. Some patients may need regular monitoring if they have chronic conditions like kidney disease or osteoporosis.
Can diet or supplements affect PTH levels?
Yes, diet and supplements like calcium, vitamin D, or magnesium can impact PTH levels. Avoiding excessive calcium intake and ensuring adequate vitamin D may help maintain balanced PTH levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy