Serum or plasma concentration of ceruloplasmin (total copper-binding protein)
This test measures the amount of ceruloplasmin in your blood, a protein that helps transport copper and plays a role in iron metabolism and antioxidant defense.
["Ceruloplasmin helps identify copper metabolism disorders or iron-related conditions."]
Key facts at a glance
- LOINC
- 15088-8
- Short code
- PTH-C SerPl-sCnc
- Synonyms
- PTH-C SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Ceruloplasmin Used For?
Ceruloplasmin levels can help diagnose or monitor conditions like Wilson’s disease (a copper storage disorder), hemochromatosis (iron overload), or other metabolic or inflammatory conditions. It may also be checked if you have symptoms of copper deficiency or unexplained iron issues.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The sample is processed to separate serum or plasma, where ceruloplasmin levels are measured using a specialized laboratory technique, often an immunoassay or similar method.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like fatigue, joint pain, liver issues, or if tests for copper or iron imbalances are abnormal. It can also be part of routine monitoring for certain genetic or metabolic disorders.
What Do Results Mean?
Results are compared to a reference range, but specific values can vary by lab. Elevated levels may suggest inflammation or certain liver conditions, while low levels could indicate copper deficiency or metabolic disorders.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Ceruloplasmin Level
Frequently asked questions
Why do I need this test?
What does a low ceruloplasmin level mean?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy