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Parathyroid Hormone (Active), Intact

Published: August 9, 2026Updated: August 17, 2026

This test measures the active form of your parathyroid hormone (PTH), a key regulator of calcium levels in your body. It helps assess whether your thyroid glands are working properly to maintain healthy blood calcium.

Quick summary

["Your doctor may order this test to check for conditions affecting calcium balance, such as hypoparathyroidism or hyperparathyroidism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
16162-0
Short code
PTH-Intact 30M p chal SerPl-mCnc
Synonyms
PTH-Intact 30M p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
80
Ref high
200
Critical range
20 N/A – 400 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Your Health

PTH plays a vital role in keeping your body’s calcium and phosphate levels balanced. Low PTH can lead to symptoms like muscle cramps, numbness, or irregular heart rhythms, while high levels may cause bone pain, kidney stones, or fatigue. This test helps identify whether your body is producing enough active PTH to support these processes.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm or hand to draw a blood sample. If you’re on blood thinners or have a history of bleeding issues, let your doctor know beforehand.

Common Conditions This Test Helps Diagnose

This test is often used to diagnose or monitor conditions like hypoparathyroidism (low PTH), hyperparathyroidism (high PTH), vitamin D deficiency, or kidney disease. It may also be checked after thyroid surgery or in cases of unexplained calcium imbalances.

What Your Results Mean

Results are interpreted by your healthcare provider based on your overall health, symptoms, and other lab values. While reference ranges vary by lab, very low or very high levels may signal underlying issues that need further evaluation.

Reference range

Adult: 80-200 ng/dLN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Parathyroid hormone (PTH) is essential for maintaining calcium homeostasis. When levels are too low, your body may struggle to absorb calcium from food or release it from bones, potentially causing muscle weakness, bone loss, or nerve damage. Conversely, high PTH can lead to calcium deposits in tissues, kidney stones, or weakened bones over time. This test helps detect imbalances early to guide treatment, such as dietary changes, vitamin D supplements, or medical interventions.

Short name

Intact PTH

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your medical history, symptoms, and treatment plan. Some people may need it once a year or more if they have ongoing conditions like kidney disease or thyroid disorders.
What are typical symptoms that might lead to this test?
Symptoms that could prompt this test include unexplained fatigue, muscle weakness or cramps, frequent bone or joint pain, numbness, or frequent kidney stones. If you’ve had thyroid surgery or have a family history of parathyroid disorders, your doctor may also recommend it.
Can diet or supplements affect PTH levels?
Yes, certain foods and supplements can influence PTH levels. High calcium intake (from dairy or supplements) or vitamin D deficiency may affect PTH regulation. Your doctor may suggest dietary adjustments or monitor PTH closely if you’re taking calcium or vitamin D supplements.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy