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Parathyroid Hormone (PTH) by Immunoassay (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of parathyroid hormone (PTH) in your blood, which helps regulate calcium and bone health.

Quick summary

["PTH levels can indicate bone health and calcium balance issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38158-2
Short code
PTH-Intact BS SerPl-mCnc
Synonyms
PTH-Intact BS SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms like bone pain, frequent fractures, or unexplained high or low calcium levels. It’s also used to diagnose or monitor conditions like hypoparathyroidism, hyperparathyroidism, or kidney disease that affect calcium metabolism.

What Does the Result Mean?

Results can vary based on your health status and medical history. High PTH levels may suggest overactive parathyroid glands, while low levels could indicate underactive glands or other conditions. Your doctor will interpret the result in the context of your symptoms and other tests.

Common Conditions Monitored

PTH levels are often checked in people with suspected or known parathyroid disorders, kidney disease, or metabolic bone diseases. It may also be used to evaluate calcium imbalances or monitor treatment for conditions like osteoporosis or Paget’s disease.

How Is the Test Done?

A blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The sample is sent to a lab for analysis using an immunoassay method to measure PTH concentration.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: PTH plays a critical role in calcium homeostasis. Elevated levels may indicate hyperparathyroidism (excess PTH production), which can lead to weakened bones, kidney stones, or heart issues. Low levels may signal hypoparathyroidism or other endocrine disorders. Regular monitoring helps manage these conditions effectively.

Short name

PTH Serum

Frequently asked questions

What does a ‘normal’ PTH level mean for me?
There’s no single ‘normal’ range for everyone—it depends on your health, age, and other factors. Your doctor will compare your result to your own baseline or lab-specific reference ranges. If your result is outside the expected range, further testing or evaluation may be needed to understand why.
How long does it take to get my results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will contact you once they’re ready, or you may receive a summary through your health portal.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor specifies otherwise. Since PTH levels can be influenced by hydration status, it’s best to follow any instructions they provide, such as fasting for other blood tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy