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Parathyroid Hormone (Active), Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the active form of parathyroid hormone (PTH), a key regulator of calcium levels in your body. It helps assess whether your thyroid glands are functioning properly to maintain healthy blood calcium.

Quick summary

["Active PTH helps balance calcium and phosphate, critical for bone health and nerve function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24346-9
Short code
PTH-Intact + Ca Pnl SerPl
Synonyms
PTH-Intact + Ca Pnl SerPl
Category
electrolyte
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like bone pain, frequent fractures, muscle weakness, or unexplained kidney stones. It’s also used to diagnose or monitor conditions such as hypoparathyroidism, hyperparathyroidism, or kidney disease that affect calcium metabolism.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results help determine if your PTH levels are too high or too low, which can indicate underlying health issues. Your doctor will compare your results to standard ranges and consider your symptoms and medical history.

Common Conditions Linked to PTH Levels

High PTH levels may suggest overactive thyroid glands (hyperparathyroidism), while low levels could indicate underactive thyroid glands (hypoparathyroidism). Kidney disease or certain medications can also affect PTH levels.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

PTH plays a vital role in regulating calcium and phosphate in your blood. When levels are abnormal, it can lead to complications like weak bones, heart problems, or nerve damage. Your doctor will use these results to guide treatment if needed.

Short name

PTH (Active)

Frequently asked questions

How often should I get this test?
This test is typically done once or twice a year if you have a chronic condition like kidney disease or hyperparathyroidism. Your doctor will determine the best timing based on your health needs.
What does an abnormal result mean?
An abnormal result means your PTH levels are outside the normal range, which may signal an issue with your thyroid or kidneys. Your doctor will discuss possible causes and next steps, such as further testing or treatment adjustments.
Can diet or supplements affect PTH levels?
Dietary calcium and vitamin D can influence PTH levels, but the test measures active PTH directly. If you’re taking supplements, let your doctor know, as they may need to adjust your treatment plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy