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Parathyroid Hormone (Active), Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the active form of parathyroid hormone (PTH), a key regulator of calcium levels in your body. It helps assess whether your thyroid glands are functioning properly.

Quick summary

["Active PTH helps balance calcium, which is vital for muscle, nerve, and bone health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108803-8
Short code
PTH-Intact Msmt SerPl
Synonyms
PTH-Intact Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like bone pain, frequent fractures, muscle weakness, or unexplained kidney stones. It’s also used to monitor conditions like hypoparathyroidism or hyperparathyroidism, or to check for calcium imbalances.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw a blood sample. The process takes a few minutes, and you may feel a brief pinch. Avoid eating or drinking for 8–12 hours before the test if instructed.

What the Results Mean

Results help determine if your PTH levels are too high or too low, which can affect calcium metabolism. High levels may suggest overactive thyroid glands, while low levels could indicate underactivity or other health issues.

Common Conditions Linked to PTH Levels

Abnormal PTH can be linked to conditions like osteoporosis, kidney disease, or vitamin D deficiencies. It’s also important for diagnosing rare disorders affecting calcium balance.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: PTH is essential for maintaining calcium and phosphate levels in your blood. High levels may indicate overproduction by the parathyroid glands, leading to conditions like hypercalcemia. Low levels can cause hypocalcemia, affecting nerves, muscles, and bones. Regular monitoring helps manage these imbalances.

Short name

PTH (Active)

Frequently asked questions

What causes abnormal PTH levels?
Abnormal PTH can result from thyroid gland disorders (e.g., hyperparathyroidism), kidney problems, vitamin D deficiency, or certain medications. Lifestyle factors like diet (low calcium or vitamin D) or genetics may also play a role.
How often should I get this test?
Your doctor will determine frequency based on your health, symptoms, or treatment plan. For example, people with chronic conditions like kidney disease may need it more often than others.
Can diet affect PTH test results?
Yes, diet can influence PTH levels. High calcium intake or vitamin D deficiency may temporarily alter results. Follow your doctor’s advice on fasting and dietary restrictions before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy