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Parathyroid Hormone (Active), Serum/Plasma Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the active form of parathyroid hormone (PTH), a key regulator of calcium levels in your blood. It helps assess whether your thyroid glands are functioning properly and if your body is maintaining healthy calcium balance.

Quick summary

["Active PTH helps diagnose conditions affecting calcium metabolism and thyroid health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90741-0
Short code
PTH-Intact SerPl IA-mCnc
Synonyms
PTH-Intact SerPl IA-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like bone pain, frequent fractures, or unexplained fatigue, or if they suspect conditions such as hyperparathyroidism (too much PTH) or hypoparathyroidism (too little PTH). It may also be used to monitor treatment for thyroid disorders or kidney disease.

How the Test Works

Blood is drawn from a vein in your arm. The sample is sent to a lab where it is analyzed using a sensitive immunoassay method to detect and measure the active PTH levels in your serum or plasma.

What to Expect Before the Test

No special preparation is needed for this test. You can eat and drink normally on the day of the test. If you are on medications that affect calcium or PTH levels, let your healthcare provider know.

What to Expect After the Test

After the blood is drawn, you may feel a slight pinch or bruising at the site. Most people recover quickly. Apply gentle pressure to the area to help stop any bleeding. Avoid vigorous activity for a short time.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High levels of active PTH can indicate hyperparathyroidism, which may lead to conditions like osteoporosis, kidney stones, or high blood calcium. Low levels may suggest hypoparathyroidism, causing symptoms such as muscle spasms, numbness, or irregular heart rhythms. Monitoring active PTH is crucial for diagnosing and managing these conditions effectively.

Short name

Active PTH

Frequently asked questions

What does an abnormal result mean?
An abnormal result may signal an imbalance in your body’s calcium regulation. Your doctor will discuss the results with you and may recommend further tests or treatments based on your symptoms and overall health.
How often should I get this test?
Your doctor will determine the frequency of testing based on your medical history, symptoms, and treatment plan. Regular monitoring may be necessary if you have chronic conditions like kidney disease or thyroid disorders.
Can diet or supplements affect this test?
Certain foods and supplements, such as calcium or vitamin D, can influence calcium levels and potentially affect PTH. It’s best to discuss any dietary changes or supplements with your healthcare provider before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy