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Parathyroid Hormone (Active), Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the active form of parathyroid hormone (PTH), a key regulator of calcium levels in your body.

Quick summary

["Active PTH helps balance calcium and phosphorus, affecting bone health and nerve function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50532-1
Short code
PTH-Intact sp8 SerPl-mCnc
Synonyms
PTH-Intact sp8 SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like bone pain, frequent fractures, or unexplained kidney stones. It’s also used to monitor conditions like hyperparathyroidism or hypoparathyroidism, or to check calcium levels in patients with kidney disease or vitamin D deficiency.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. Avoiding certain foods or supplements (like calcium or vitamin D) for 48 hours before testing may help ensure accurate results, but always follow your doctor’s instructions.

What the Results Mean

High active PTH levels may indicate overactive parathyroid glands or conditions affecting calcium metabolism. Low levels could suggest underactive thyroid or other hormonal imbalances. Your doctor will interpret results in relation to your overall health and symptoms.

Common Conditions Monitored

This test is critical for diagnosing or managing hypercalcemia (high calcium), hypocalcemia (low calcium), or parathyroid disorders. It’s also used in patients with chronic kidney disease or metabolic bone diseases.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Active PTH is a more precise marker than total PTH because it reflects the biologically active form of the hormone. Abnormal levels can signal underlying issues like kidney disease, vitamin D deficiency, or primary hyperparathyroidism, which may require medical treatment or lifestyle adjustments.

Short name

Active PTH

Frequently asked questions

What causes abnormal active PTH levels?
Active PTH levels can be elevated due to overactive parathyroid glands (hyperparathyroidism), kidney disease, or vitamin D deficiency. Low levels may result from hypoparathyroidism, thyroid disorders, or certain medications.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your doctor will contact you once they’re ready for review.
Can diet affect active PTH levels?
Yes, dietary calcium, vitamin D, and protein intake can influence PTH levels. Avoiding high-calcium foods or supplements for 48 hours before testing may improve accuracy, but always follow your healthcare provider’s guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy