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Parathyroid Hormone (PTH) by Immunoassay (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood level of parathyroid hormone, a protein that helps regulate calcium and phosphorus in your body.

Quick summary

["PTH helps balance calcium, which is vital for bone health and nerve function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44137-8
Short code
PT Hrt W RNC IV
Synonyms
PT Hrt W RNC IV
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
pt
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for conditions affecting calcium levels, such as hypoparathyroidism (low PTH), hyperparathyroidism (high PTH), or kidney disease. It can also help diagnose or monitor conditions like osteoporosis, rickets, or pseudohypoparathyroidism.

What Does the Test Measure?

PTH is a hormone produced by the parathyroid glands. It signals your bones to release calcium into your bloodstream and helps your kidneys remove extra phosphorus. Abnormal levels can indicate issues with calcium metabolism or gland function.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed using an immunoassay method to detect PTH levels.

What Are Common Causes of Abnormal Results?

Low PTH levels may be due to thyroid disease, kidney problems, or surgical removal of the parathyroid glands. High PTH levels could result from overactive parathyroid glands, kidney failure, or certain cancers.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing and managing conditions that disrupt calcium balance, helping doctors tailor treatments like vitamin D supplements, medications, or surgery to restore normal hormone levels.

Short name

PTH (Serum)

Frequently asked questions

What might cause my PTH levels to be too high or too low?
High PTH levels can be caused by conditions like primary hyperparathyroidism, kidney disease, or certain medications. Low PTH levels may result from thyroid disorders, vitamin D deficiency, or surgical removal of the parathyroid glands. Your doctor will discuss these findings with you during your follow-up.
How often should I have this test?
The frequency depends on your health condition and treatment plan. Your doctor will determine how often you need retests, often based on symptoms, medical history, and other test results.
Can lifestyle changes affect PTH levels?
Yes, diet and lifestyle can influence calcium and vitamin D levels, which may indirectly affect PTH. Staying hydrated, eating a balanced diet rich in calcium and vitamin D, and avoiding excessive salt can support overall calcium balance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy