Protein Electrophoresis on Serum (Qualitative)
This test measures the different types of proteins in your blood using gel electrophoresis, a method that separates proteins based on size and charge. It helps identify abnormalities in protein distribution, which can signal conditions like multiple myeloma, liver disease, or kidney problems.
["This test helps doctors diagnose and monitor conditions affecting protein levels in your blood."]
Key facts at a glance
- LOINC
- 57822-9
- Short code
- PT Lung W RNC IV
- Synonyms
- PT Lung W RNC IV
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- pt
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Electrophoresis separates blood proteins into fractions—such as albumin, globulins, and other proteins—based on their electrical charge and size. Each fraction appears as distinct bands on a gel. Abnormal patterns may indicate conditions like chronic inflammation, infections, or genetic disorders.
Why Might Your Doctor Order This Test?
Your doctor may recommend this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect conditions like multiple myeloma, liver disease, or kidney disease. It’s also used to monitor treatment progress for certain blood disorders.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The serum (liquid part of blood after clotting) is then applied to a gel and subjected to an electric current. Proteins migrate through the gel, creating visible bands that are analyzed.
What Are Common Findings?
Normal results show distinct bands representing balanced protein types. Abnormal findings may include: - **Monoclonal spikes** (extra bands suggesting multiple myeloma or other plasma cell disorders). - **Reduced albumin** (possible liver or kidney disease). - **Increased globulins** (could indicate chronic infections or autoimmune conditions).
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test plays a key role in diagnosing and managing blood-related disorders. For example, a monoclonal spike may prompt further testing for conditions like multiple myeloma, while abnormal protein patterns can guide treatment plans for chronic illnesses. It’s also useful for monitoring protein levels over time.
Short name
Serum Protein Electrophoresis (Qual)
Frequently asked questions
What does a ‘qualitative’ result mean?
How long does it take to get results?
Can diet or medications affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy