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Perfusion Index (Perfusion Rate) via Multiplexed Exhaled Breath Analysis

Published: August 9, 2026Updated: August 16, 2026

This test measures how well different areas of your lungs are receiving blood flow, using exhaled breath samples. It may help assess lung function or circulation in specific regions.

Quick summary

["This test evaluates lung perfusion efficiency through breath analysis—useful for detecting uneven blood flow in the lungs."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81568-8
Short code
PT.perfusion Hrt W mult exer
Synonyms
PT.perfusion Hrt W mult exer
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
pt-perfusion
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The perfusion index evaluates how effectively your lungs receive blood flow, broken down by region. This is done by analyzing chemical markers in exhaled breath, which reflect blood flow dynamics in the lungs. This method is often used in specialized settings to detect abnormalities in perfusion without invasive procedures.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms like shortness of breath, suspected lung conditions (e.g., pulmonary embolism, chronic obstructive pulmonary disease), or if monitoring lung function is needed during certain treatments. It can also help assess perfusion in patients with known vascular or lung diseases.

Sample Collection and Preparation

You’ll exhale into a specialized device that collects and analyzes your breath over a set period. No fasting or special preparation is required, but follow your provider’s instructions for timing. The test is typically quick and painless, with no needles or blood draws involved.

What to Expect During the Test

You’ll sit comfortably while exhaling into a mouthpiece connected to a machine. The device measures breath composition in real time, often taking just a few minutes. You may be asked to breathe deeply or hold your breath briefly to ensure accurate results.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal perfusion indices may indicate conditions like pulmonary embolism (blocked blood flow in the lungs), lung diseases (e.g., fibrosis), or vascular issues affecting lung circulation. Low perfusion in certain areas could signal reduced blood flow, which may require further investigation or treatment adjustments. This test is particularly useful for monitoring patients with known perfusion disorders or during diagnostic evaluations.

Short name

Perfusion Index (Exhaled Breath)

Frequently asked questions

How long does it take to get results?
Results are usually available within a few hours to a couple of days, depending on lab processing times. Your healthcare provider will discuss the findings with you during your follow-up visit.
Is this test painful or uncomfortable?
No, this test is completely painless. You simply exhale into a device, similar to breathing into a mouthpiece during a routine checkup. There are no needles, injections, or discomfort involved.
Can I eat or drink before this test?
No special preparation is needed. You can eat, drink, or take medications as usual. However, always follow any specific instructions your healthcare provider gives you before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy