Serum/plasma maximum reversal rate of pulmonary vasoconstrictor activity (e.g., vasodilator response assessment)
This test measures how effectively your blood vessels in the lungs relax in response to a vasodilator, which helps assess lung function and blood flow in conditions like pulmonary hypertension.
["Evaluates lung blood vessel responsiveness to help diagnose or monitor lung-related vascular conditions."]
Key facts at a glance
- LOINC
- 29453-8
- Short code
- Pulm v A-wave reversal.max DOP
- Synonyms
- Pulm v A-wave reversal.max DOP
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- us-doppler
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is This Test Measuring?
This test evaluates the maximum rate at which your blood vessels in the lungs constrict or relax in response to a vasodilator medication. It helps determine how well your lungs handle blood flow and pressure, which is critical for diagnosing or managing conditions like pulmonary hypertension or other vascular lung diseases.
Why Might You Need This Test?
Your doctor may order this test if you have symptoms like shortness of breath, fatigue, or if they suspect a condition affecting your lung blood vessels. It can also be used to monitor treatment progress in patients with known vascular lung diseases.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The sample is processed to separate plasma or serum, which is then analyzed to measure the vasodilator response. This process typically takes place in a clinical lab.
Preparation for the Test
No special preparation is needed for this test. However, inform your healthcare provider about any medications you are taking, especially those affecting blood pressure or heart function, to ensure accurate results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is primarily used to assess the functional integrity of pulmonary vasculature. A reduced reversal rate may indicate impaired lung blood vessel responsiveness, which can be associated with conditions such as pulmonary hypertension, chronic obstructive pulmonary disease (COPD), or other vascular lung disorders. It helps guide treatment decisions and monitor disease progression.
Short name
Vasodilator Response Test (Pulmonary Vasoconstriction Reversal)
Frequently asked questions
What Does a High or Low Result Mean?
How Long Does It Take to Get Results?
Is This Test Painful or Discomforting?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy