Purkinje Cell Antibody Screening (Serum)
This test checks for antibodies that may be linked to certain autoimmune conditions affecting the nervous system, including those that could affect movement or coordination.
["This screening helps identify potential autoimmune responses that may require further evaluation."]
Key facts at a glance
- LOINC
- 14249-7
- Short code
- Purkinje Cells Ab Ser Ql IF
- Synonyms
- Purkinje Cells Ab Ser Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects the presence of antibodies directed against Purkinje cells, which are specialized nerve cells in the cerebellum—a region of the brain responsible for balance and coordination. These antibodies may be associated with conditions like cerebellar ataxia or other neurological disorders.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms such as unsteady walking, difficulty with fine motor skills, or other signs of cerebellar dysfunction. It can also be part of an evaluation for autoimmune diseases affecting the nervous system.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The serum portion of your blood is separated and sent to the lab for testing. This process is typically done in a clinical setting by a trained healthcare professional.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to avoid certain medications or foods that could interfere with results. Always inform your provider about all medications, supplements, or recent illnesses.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results may indicate an autoimmune response targeting Purkinje cells, which could suggest conditions like cerebellar ataxia, autoimmune encephalitis, or other neurological autoimmune disorders. Further testing and evaluation by a specialist may be required to determine the exact cause and appropriate treatment.
Short name
Purkinje Cell Antibody Screen
Frequently asked questions
What does a positive result mean?
Can this test be used to diagnose a specific disease?
How often should this test be repeated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy