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C-reactive protein (CRP) with 24-hour urine collection for end-of-treatment monitoring

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein in your urine over 24 hours to assess inflammation, often used to monitor treatment response in conditions like infections or autoimmune diseases.

Quick summary

["CRP helps track how well your body’s inflammation is responding to ongoing treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111855-3
Short code
Purpose of treatment Endscpy
Synonyms
Purpose of treatment Endscpy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
endoscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to evaluate whether your ongoing treatment for inflammation or infection is working effectively. It helps determine if the condition is improving or if adjustments to your treatment plan are needed.

What to Expect Before the Test

You’ll collect urine for 24 hours in a special container. Make sure to record the time each urine sample is voided to ensure accurate measurement. Avoid foods or supplements that may affect CRP levels, as instructed by your doctor.

How the Test Works

The collected urine is analyzed to measure CRP, a protein produced by the liver in response to inflammation. This test provides a comprehensive picture of systemic inflammation over a full day.

Possible Results and Next Steps

Results may indicate persistent or reduced inflammation. Your doctor will discuss findings with you and may recommend follow-up tests or treatment adjustments based on the outcome.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP is a marker of inflammation and is often used alongside other tests to guide treatment decisions. Elevated levels may suggest ongoing inflammation, while lower levels may indicate treatment success. This test helps ensure your treatment is effective and adjusts care as needed.

Short name

CRP Urine End-of-Treatment

Frequently asked questions

What does a high CRP level in urine mean?
A high CRP level in urine may indicate persistent inflammation or infection, which could mean your treatment needs to be reviewed or adjusted. Your doctor will discuss this with you during your follow-up.
The frequency depends on your treatment plan. Your healthcare provider will let you know how often this test should be done, typically as part of ongoing monitoring for your condition.
Some foods, supplements, or medications may influence CRP levels. Follow your doctor’s instructions on what to avoid before the test to ensure accurate results.
If you miss a sample, contact your healthcare provider immediately to reschedule or adjust the collection period. Missing samples can lead to inaccurate results.
No, this test involves collecting urine over 24 hours, which is typically done at home. There are no injections, needles, or discomfort associated with this procedure.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy