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Serum Anti-Pneumococcal Antibody Titration (Qualitative or Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures your immune response to pneumococcal bacteria by detecting antibodies in your serum. It helps assess protection against serious infections caused by these bacteria.

Quick summary

["Checks if your body has produced antibodies against pneumococcal bacteria for protection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104437-9
Short code
PV1 Ab sp2 Titr Ser IA
Synonyms
PV1 Ab sp2 Titr Ser IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for specific antibodies (immunoglobulins) your immune system creates in response to exposure to pneumococcal bacteria. These antibodies are part of your defense against infections like pneumonia, bloodstream infections, or meningitis caused by these bacteria. The result may be qualitative (yes/no presence) or quantitative (level of antibodies).

Why It’s Ordered

Your healthcare provider may order this test if you’ve had recent or ongoing symptoms of pneumococcal infections, if you’re at high risk (e.g., due to age, chronic illness, or weakened immune system), or if you’re planning vaccination to ensure your immune response is adequate.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate serum (the liquid part without clots), which is then tested for antibodies. This process typically takes a few hours to complete in the lab.

Interpretation and Results

Results are interpreted based on whether antibodies are present and their concentration. A positive result indicates your immune system has recognized and responded to the bacteria. The clinical significance depends on your medical history and risk factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Pneumococcal Antibody Test

Frequently asked questions

How long will it take to get my results?
Results are usually available within 24 to 72 hours, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
What does a positive or negative result mean?
A positive result means your body has produced antibodies against pneumococcal bacteria, suggesting some level of immunity. However, this does not guarantee protection against all strains. A negative result means no detectable antibodies, which may indicate no prior exposure or a weak immune response. Your provider will interpret results in the context of your health and vaccination history.
Can I get this test if I’ve had the pneumococcal vaccine?
Yes, this test can be used to evaluate your immune response after vaccination. It helps determine if the vaccine was effective in stimulating your immune system to produce antibodies against pneumococcal bacteria.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy