Protein Electrophoresis on Serum/Plasma (Qualitative)

What Does This Test Measure?

Protein electrophoresis separates blood proteins into distinct bands based on size and charge. This includes albumin, globulins (such as immunoglobulins), and other proteins like fibrinogen. The qualitative result provides a visual profile rather than specific numeric values for each protein fraction.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like swelling, unexplained weight loss, fatigue, or if they suspect conditions such as multiple myeloma, lymphoma, kidney disease, or liver disease. It can also help monitor treatment progress for certain protein-related disorders.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is sent to the lab for electrophoresis. The test does not require fasting, but follow your doctor’s specific instructions for preparation.

Common Conditions Evaluated

This test is often used to detect abnormal protein patterns, such as monoclonal spikes (seen in multiple myeloma), hypoalbuminemia (low albumin), or elevated globulin levels. It can also help identify conditions affecting protein synthesis or breakdown in the body.