Skip to content

Prothrombin Time (PT) with International Normalized Ratio (INR) - Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures how long it takes for blood to clot, helping assess blood clotting function and detect issues like bleeding disorders or clotting problems.

Quick summary

["PT/INR helps monitor blood thinners and check for clotting abnormalities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24171-1
Short code
PV2 NAb sp1 Titr Ser Nt
Synonyms
PV2 NAb sp1 Titr Ser Nt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
neut
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order a PT/INR test to evaluate how well your blood clots normally. It’s often used to monitor medications like warfarin (Coumadin) that prevent blood clots. It can also help diagnose conditions that affect clotting, such as liver disease or bleeding disorders.

How the Test Works

A small amount of your blood is drawn and mixed with a special solution. The time it takes for a clot to form is measured and compared to a standard reference. The INR converts this time into a standardized value for interpretation.

What to Expect Before the Test

No special preparation is needed unless your doctor instructs otherwise. You may be asked to avoid certain medications or foods that could affect clotting, such as vitamin K-rich foods (like leafy greens) if you’re on blood thinners.

What to Expect During the Test

The test involves a quick blood draw from a vein in your arm. You may feel a small pinch, but it usually takes only a few minutes. The blood is sent to a lab for analysis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High PT/INR levels may indicate bleeding disorders, liver disease, or excessive use of blood-thinning medications. Low levels could suggest clotting problems or vitamin K deficiency. Monitoring PT/INR is critical for patients on anticoagulant therapy to prevent excessive bleeding or clotting.

Short name

PT/INR

Frequently asked questions

What does a high PT/INR mean?
A high PT/INR suggests your blood may clot more slowly than usual, which could be due to liver disease, vitamin K deficiency, or medications like warfarin. Your doctor will discuss this with you and may adjust your treatment plan.
What does a low PT/INR mean?
A low PT/INR may indicate your blood clots too quickly, which can be a risk for clots forming in your veins or arteries. This could happen with certain medications or genetic clotting disorders. Your doctor will review your results and consider other factors.
Can diet affect PT/INR results?
Yes, certain foods high in vitamin K (like green leafy vegetables, some fruits, and certain oils) can affect PT/INR. If you’re on blood thinners, your doctor may recommend limiting these foods or monitoring your intake to keep your results stable.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy