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Pyruvate and Creatinine, Urine — Mass Concentration, Turbidimetric

Published: August 9, 2026Updated: August 16, 2026

Measures pyruvate and creatinine in urine. Creatinine helps account for urine concentration, making pyruvate levels easier to interpret.

Quick summary

["This urine test evaluates pyruvate relative to the concentration of the urine sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108534-9
Short code
Pyruvate/Creat Msmt Ur
Synonyms
Pyruvate/Creat Msmt Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures pyruvate, a substance produced during energy metabolism, along with creatinine in urine. Creatinine is commonly used to help account for how concentrated the urine is.

Why might I need this test?

A clinician may order this test when evaluating unusual pyruvate levels or suspected problems with energy metabolism. It may also be used to follow certain metabolic or mitochondrial conditions over time.

How is the test performed?

A urine sample is collected according to the laboratory's instructions. The laboratory measures the amounts of pyruvate and creatinine using a validated mass-based method and may report them separately or as a relative value.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional, including whether a first-morning, random, or timed urine sample is required. Record the collection time and complete the sample within the specified time frame.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine pyruvate and creatinine

Frequently asked questions

What does urine pyruvate measure?
Urine pyruvate measures the amount of this energy-metabolism byproduct excreted in your urine. The result is interpreted alongside creatinine and other clinical findings.
Why is creatinine included with pyruvate?
Creatinine reflects urine concentration and helps show whether a pyruvate value is influenced by a very dilute or concentrated sample. A relative pyruvate-to-creatinine result may be easier to interpret than pyruvate alone.
Does an abnormal result mean I have a metabolic disorder?
No. An abnormal result can have several causes and does not by itself establish a metabolic or mitochondrial disorder. Your clinician will consider symptoms, medications, collection conditions, and other laboratory results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy