Total Protein with Albumin/GLOBulin Separation (Serum)

Why This Test Matters

Your body produces proteins in different forms, each serving unique roles. Albumin, the most abundant protein, helps keep fluids in your blood vessels and carries important substances like hormones and vitamins. Globulins include antibodies (for immunity), clotting factors, and other proteins that help fight infections and support immune responses. Together, these proteins contribute to overall health and disease prevention.

How the Test Works

A small blood sample is drawn and sent to a lab. The serum is analyzed using a specialized method to separate and measure albumin and globulin levels. This helps identify imbalances that may signal underlying health issues.

Common Conditions Affecting Protein Levels

Low total protein or abnormal albumin/globulin ratios can signal conditions such as malnutrition, liver disease (reduced albumin), chronic infections (increased globulins), or kidney disease (protein loss in urine). High globulin levels may indicate autoimmune disorders or chronic inflammation.

What to Expect Before the Test

No special preparation is needed, but inform your healthcare provider about any medications, recent illnesses, or conditions that might affect protein levels (e.g., kidney disease, liver issues, or infections). Avoid heavy meals 2 hours before the draw.