Quantitative measurement of offset time in a reflexive (reaction time-based) immunoassay test for antibody detection
This test measures how long it takes for a specific reaction to occur in an antibody test, often used to confirm or screen for certain immune responses.
["This test helps assess how quickly your immune system reacts to specific substances in your blood."]
Key facts at a glance
- LOINC
- 18514-0
- Short code
- QRS Offset Time RefB
- Synonyms
- QRS Offset Time RefB
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ekg
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test evaluates the time delay (offset) in an immunoassay process, which detects antibodies. This timing can vary depending on the concentration of antibodies present or the sensitivity of the assay method. It’s sometimes used alongside other tests to refine results, such as screening or confirming conditions like autoimmune diseases or infections.
Why It Might Be Ordered
Your healthcare provider may order this test if they suspect an immune-related condition, such as an infection, autoimmune disorder, or allergy. The offset time can help determine if antibodies are present at a detectable level or if further testing is needed.
Common Uses in Healthcare
This test is often used in conjunction with other immunoassays to improve accuracy. For example, it may be part of a screening process to identify early signs of conditions like chronic inflammation or certain infections where antibody presence is suspected.
What to Expect Before the Test
No special preparation is typically required for this test. You may have a blood sample drawn from a vein in your arm, similar to other blood tests. If the test involves a urine sample, you might be asked to collect a midstream urine specimen.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
What does an abnormal offset time mean?
How is this test different from standard antibody tests?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy