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Hemoglobin A1c (HbA1c) with 24-hour urine collection for creatinine clearance calculation

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar levels over the past 2–3 months and estimates how well your kidneys filter blood, using a 24-hour urine sample.

Quick summary

["Helps track diabetes management and kidney function together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9983-8
Short code
QRS T-Amp L-V5
Synonyms
QRS T-Amp L-V5
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Diabetes Care

HbA1c reflects your blood sugar control over time, while creatinine clearance assesses kidney function. Together, they provide a fuller picture of your health, especially if you have diabetes or kidney concerns.

How the Test Works

Your blood is tested for HbA1c to measure long-term sugar levels. A 24-hour urine sample is analyzed for creatinine to estimate how well your kidneys remove waste from your blood.

What to Expect Before the Test

No special preparation is needed for the blood draw, but you’ll collect a full 24-hour urine sample starting after your first morning urine. Drink plenty of water to help your kidneys filter urine properly.

Common Causes for This Test

This test may be ordered if you have diabetes to monitor both blood sugar and kidney health, or if you have symptoms like frequent urination, fatigue, or swelling that might indicate kidney issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HbA1c + CrCl (24h urine)

Frequently asked questions

What does an abnormal result mean?
High HbA1c levels may indicate poor blood sugar control, while abnormal creatinine clearance could signal kidney problems. Your doctor will discuss results with you and adjust care plans as needed.
How often should I get this test?
Your doctor will determine frequency based on your diabetes management plan or kidney health. Follow-up may be scheduled yearly or more often if needed.
Can I eat or drink before the urine collection?
Yes, but avoid excessive caffeine or alcohol, as they can affect urine clarity. Drink normal fluids unless instructed otherwise.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy