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Quinine concentration in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of quinine, a medication used to treat severe malaria, in your blood plasma. It helps monitor your drug levels to ensure proper dosing and avoid potential side effects.

Quick summary

This test helps doctors check if your quinine dose is working correctly and at safe levels.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73177-8
Short code
quiNINE ind plt IgG SerPl Ql FC
Synonyms
quiNINE ind plt IgG SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking quinine to treat or prevent malaria. It’s particularly important for people with kidney issues or those taking other medications that interact with quinine. The test helps adjust your dose to stay within safe ranges and prevent toxicity.

How the Test Works

A blood sample is taken from a vein in your arm. The plasma portion of your blood is then analyzed using a specialized laboratory method to measure quinine concentration. The result is compared to a reference range to determine your current level.

What to Expect Before the Test

No special preparation is needed, but let your doctor know if you’re taking other medications, have allergies, or are pregnant. Avoid eating or drinking anything (except water) for a few hours before the test if instructed.

What to Expect During the Test

The test involves a small needle inserted into your arm to draw blood. You may feel a slight pinch, but it usually doesn’t cause discomfort. The process takes about 5 minutes, and you can resume normal activities afterward.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High quinine levels may indicate overdose or improper dosing, which can cause side effects like dizziness, nausea, or heart rhythm changes. Low levels could mean the medication isn’t working effectively, requiring dose adjustments. Regular monitoring is especially important for people with kidney problems or those taking other drugs that interact with quinine.

Short name

Quinine Level

Frequently asked questions

How long does it take to get the results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the results with you during your follow-up visit.
What does a normal range mean for this test?
There isn’t a single universal reference range for quinine levels because it varies based on factors like your weight, kidney function, and the reason for testing. Your doctor will interpret the result in relation to your specific situation and medical needs.
Can I eat or drink before this test?
Follow your doctor’s instructions, but generally, you should avoid food for 2–4 hours before the test if they specify it. Drink water as usual unless told otherwise.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy