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Serum/plasma mass concentration of total protein

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, including albumin and other proteins like globulins.

Quick summary

["Total protein helps assess overall protein balance and potential nutritional or kidney issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9930-9
Short code
Q wave Dpth L-III
Synonyms
Q wave Dpth L-III
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein levels, such as malnutrition, kidney disease, liver problems, or certain infections. It can also help evaluate fluid balance or diagnose conditions like edema (swelling) or protein-losing syndromes.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein (usually in your arm) to draw blood. If you’re using blood thinners, let your provider know beforehand.

What Happens During the Test?

A healthcare professional will collect a blood sample, which is then sent to a lab for analysis. The test typically takes a few minutes to complete.

What Are Possible Results?

Results are compared to a general reference range, but exact values can vary by lab. Low protein levels may indicate poor nutrition, kidney or liver disease, or excessive protein loss. High levels could suggest dehydration, inflammation, or conditions like multiple myeloma.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein levels can signal underlying health issues. Low protein may point to malnutrition, chronic kidney disease, or liver dysfunction, while high protein could indicate dehydration, severe infections, or certain cancers. Regular monitoring helps manage these conditions effectively.

Short name

Total Protein

Frequently asked questions

What causes low protein levels?
Low protein levels can result from poor nutrition (e.g., not eating enough protein-rich foods), kidney disease (which filters proteins), liver disease (which produces proteins), or conditions causing excessive protein loss (e.g., severe diarrhea, protein-losing enteropathy).
What causes high protein levels?
High protein levels may occur due to dehydration, severe infections or inflammations, or certain cancers (like multiple myeloma). Rarely, it can be genetic or linked to conditions affecting protein breakdown.
How often should I get this test?
Your provider will determine how often you need this test based on your health status. For example, people with kidney or liver disease may need it more frequently, while others may only need it occasionally.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy