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Serum or plasma concentration of **D-dimer** (mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of D-dimer, a breakdown product formed when blood clots dissolve. It helps assess whether abnormal clotting or clot-dissolving processes may be occurring in your body.

Quick summary

["D-dimer helps diagnose or monitor blood clotting disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9931-7
Short code
Q wave Dpth L-V1
Synonyms
Q wave Dpth L-V1
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is D-Dimer Used For?

D-dimer is primarily used to evaluate conditions involving blood clots or clot breakdown. It can assist in diagnosing deep vein thrombosis (blood clots in veins), pulmonary embolism (clots in the lungs), or other clotting disorders. It may also be used in certain types of cancer or after surgery to monitor clot risk.

How Is the Test Performed?

A small blood sample is drawn from your arm, typically in the morning after fasting. The blood is processed to separate serum or plasma, where D-dimer levels are measured using an immunoassay method. Results are reported in arbitrary units concentration (e.g., ng/mL).

What Are Common Reasons for Testing?

Your healthcare provider may order a D-dimer test if you have symptoms like leg swelling, chest pain, shortness of breath, or if you’ve been diagnosed with a condition that increases clot risk, such as cancer, heart disease, or recent surgery.

What Do Results Mean?

High D-dimer levels suggest recent clot formation or breakdown, which may indicate conditions like deep vein thrombosis or pulmonary embolism. Very low levels are normal. Your doctor will interpret results in the context of your symptoms and medical history.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: D-Dimer plays a key role in identifying or ruling out blood clots. While a positive test strongly suggests clotting activity, it’s not definitive on its own. Doctors may use it alongside other tests (like imaging) to guide treatment decisions, such as anticoagulant therapy for clots.

Short name

D-Dimer

Frequently asked questions

Why might my doctor recommend this test?
Your doctor may recommend this test to check for blood clots in your legs, lungs, or other areas, especially if you have symptoms like swelling, pain, or breathing difficulties. It could also be used after surgery or in cases where cancer or other conditions increase clot risk.
What if my D-dimer level is high?
A high D-dimer level often points to recent clot formation or breakdown, which may require further testing (like imaging) to confirm the cause. Your doctor may recommend blood thinners or other treatments if clots are suspected.
Can I eat or drink before this test?
For most D-dimer tests, you may eat and drink normally unless instructed otherwise. However, fasting is not typically required, but check with your provider for any specific guidelines.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy