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C-reactive protein (CRP) concentration, serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify and monitor inflammation, often used to check for infections, autoimmune conditions, or other health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9934-1
Short code
Q wave Dpth L-V4
Synonyms
Q wave Dpth L-V4
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ekg
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP Matters in Your Health

CRP is a marker that signals your body is fighting inflammation. High levels may indicate infections like pneumonia or urinary tract infections, or conditions such as rheumatoid arthritis or heart disease. Your doctor may order this test to assess risk, track treatment progress, or investigate unexplained symptoms.

When This Test Is Done

CRP tests are often performed during routine check-ups, after an injury or surgery, or when symptoms like fever, joint pain, or fatigue appear. Doctors may also use it to monitor chronic conditions like heart disease or autoimmune disorders.

How the Test Works

A small blood sample is taken from a vein, usually in your arm. The blood is sent to a lab where it is analyzed to measure CRP levels. The test is quick and typically done without preparation.

What to Expect Before or After the Test

You may need to fast for 8–12 hours before the test if instructed, but CRP tests often don’t require fasting. After the draw, you might feel slight discomfort at the injection site, but it usually goes away quickly. Avoid strenuous activity for a few hours afterward.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated CRP levels often point to inflammation, which can be caused by infections, injuries, or inflammatory diseases. While CRP alone doesn’t diagnose a specific condition, it helps guide further testing or treatment decisions. Low or normal levels suggest minimal inflammation, but they don’t rule out all causes of symptoms.

Short name

CRP

Frequently asked questions

What does a high CRP level mean?
A high CRP level may signal inflammation, which could be due to infections, autoimmune diseases, or other health problems like heart disease. Your doctor will consider your symptoms, medical history, and other test results to determine the cause.
What does a low CRP level mean?
A low CRP level usually means there is little to no inflammation detected in your blood. However, it doesn’t rule out all possible causes of symptoms or underlying conditions, so further evaluation may still be needed.
Can CRP levels change with diet or exercise?
Yes, lifestyle factors like diet, exercise, and stress can influence inflammation levels. Certain foods, such as those high in omega-3 fatty acids or anti-inflammatory spices, may help reduce CRP, while poor diet or lack of movement can worsen it. Talk to your doctor about how to support your health through diet and activity.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy